General Clinical Chemistry Analyzers and Accessories
Abcam IMR-1, 25MG
MW 353.4 Da, Purity =99%. Notch pathway inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Roche Diagnostics Sodium Bio HT, 200 tests
Kit for determination of sodium. This product is intended for quantitative determination of sodium in aqueous solutions using the Cedex Bio HT Analyzer.
Perkin Elmer US LLC Sipper Cell and Pump Accessory
The Sipper Cell and Pump Accessory measures large numbers of liquid samples quickly and accurately. Samples can be transferred from a wide variety of containers to the flow cell. Includes: Synthetic Fused Silica flow cell, pathlength: 1.3 mm, cell volume: 16 mL (L2151247) Peristaltic pump controlled by computer Standard fitting 0.4 mm FEP Inlet Tube (L2151202) 0.7 mm FEP Outlet Tube (L2151203) Please note: This accessory requires installation by a PerkinElmer service engineer, not included.
Abcam Fluo-4 AM, Fluorescent labeling reagent, 10 x 50UG
Fluo-4 AM, Fluorescent labeling reagent (ab241082) is part of the reagents, controls & accessories range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB-525334, TGFBR1 inhibitor., 5MG
MW 343.4 Da, Purity >98%. Cell permeable, potent, selective transforming growth factor beta 1 receptor (ALK5) (IC₅₀ = 14.3 nM) and ALK4 (IC₅₀ = 58.5 nM) inhibitor, with no activity at ALK2, 3 and 6 (IC₅₀ > 10 μM). Blocks fibrosis and renal injury markers in a puromycin-induced nephritis model. Causes significant attenuation in Smad2/3 nuclear translocation and a decrease in CTGF-expressing cells, myofibroblast proliferation and type 1 collagen deposition resulting in an overall attenuation in bleomycin-induced pulmonary fibrosis.
The product is subject to the following: Abcam Restricted Use Statement
Abcam LM22A-4, neurotrophic BDNF mimetic, 50MG
MW 339.34 Da, Purity >98%. Small molecule BDNF mimetic displaying neurotrophic activity. Partial agonist at TrkB, activating TrkB signaling. Displaces BDNF (IC₅₀ = 47 nM) in binding assays. Prevents neuronal degeneration with equal efficacy to that of BDNF in in vitro models of neurodegenerative disease. Causes hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats, after in vivo administraton. Improves respiratory function in a mouse model of Rett syndrome.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AZ-20, 25MG
MW 412.5 Da. Potent and selective ATR kinase inhibitor (IC₅₀ = 5 nM in vitro; IC₅₀ = 50 nM in carcinoma cell lines). Selective versus mTOR (8-fold). Displayed selectivity versus a panel of 442 kinases.Inhibits LoVo colorectal adenocarcinoma tumor cell growth.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PF-573228, 10MG
MW 491.5 Da, Purity >=98%. Potent and selective FAK inhibitor (IC₅₀ = 4 nM versus recombunant catalytic fragent). Blocks FAK Tyr397phosphorylation in cultured cells (IC₅₀ = 30–100 nM). Shows 50 - 250-fold selectivity for FAK aginst a panel of 40 recombinant kinases. Inhibits chemotactic and haptotactic cell migration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ispinesib (SB-715992), 5MG
MW 517.1 Da, Purity >98%. A potent, selective and reversible allosteric inhibitor of KSP with IC₅₀ value of 0.5 nM. Often combines with chemotherapy drugs to tumor treatment.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Prostaglandin A1, 5MG
MW 336.5 Da. Endogenous prostaglandin with diverse biological actions including anti-hypertensive, anti-inflammatory, anti-viral and anti-cancer properties.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sitravatinib, 25MG
MW 629.7 Da, Purity =98%. Broad spectrum receptor tyrosine kinase inhibitor (e.g. Axl, c-Met, PDGFR, VEGFR, Ephrin receptor family, and FLT3). Better efficacy in mouse models than imatinib and crizotinib.
The product is subject to the following: Abcam Restricted Use Statement
Abcam D-Gluconic acid, methyl ester, 50MG
MW 210.18 g/mol. Membrane permeant analog of D-gluconic acid. Useful as a component of cell culture media; enzymatic degradation of xylan and glucomannan; various pharmaceutical preparations; as well as an intermediate in carbohydrate based synthetic preparations of sugar derivatives.
The product is subject to the following: Abcam Restricted Use Statement